Journal of Operational Research and Its Applications ( Applied Mathematics ) - Lahijan Azad University

       This paper presents a multi-group model of COVID-19, categorizing the population into four compartments: susceptible, asymptomatic infective, symptomatic infective, and recovered. We investigate the disease-free equilibrium and the basic reproduction number. Through targeted interventions, primarily focused on reducing asymptomatic and symptomatic cases, we aim to effectively control and potentially eliminate the disease in certain regions. Empirical data from Isfahan, Khorasan-Razavi, and Fars provinces are utilized to validate the model's effectiveness. In the images obtained from the simulation results, it can be seen that the spread of the disease has been controlled by the controllers, and the number of infected people without symptoms and infected people with symptoms has been greatly reduced.